PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14551349-13 2003 Heparin inhibited NF-kappaB activation in Ang II-stimulated MCs that expressed either normal or chemically altered GAG. Glycosaminoglycans 115-118 nuclear factor kappa B subunit 1 Homo sapiens 18-27 34768285-4 2022 We found that AT competitively inhibits the GAG-dependent HRPII-mediated activation of NF-kappaB and expression of intercellular cell adhesion molecule 1 (ICAM1) in endothelial cells. Glycosaminoglycans 44-47 nuclear factor kappa B subunit 1 Homo sapiens 87-96 32466274-6 2020 Furthermore, investigations regarding the mechanism of anti-inflammatory activity of GAG were focused on nuclear transcription factor-kB (NF-kappaB)-related signal transduction. Glycosaminoglycans 85-88 nuclear factor kappa B subunit 1 Homo sapiens 138-147 32466274-7 2020 Immunofluorescence staining of the p65 subunit of NF-kappaB and immunoblotting were performed that showed a significant decrease in NF-kappaB level in macrophages on GAG-based multilayers. Glycosaminoglycans 166-169 nuclear factor kappa B subunit 1 Homo sapiens 50-59 32466274-10 2020 The results provide an insight on the anti-inflammatory effects of GAG not only based on their physicochemical properties, but also related to their mechanism of action toward NF-kappaB signal transduction. Glycosaminoglycans 67-70 nuclear factor kappa B subunit 1 Homo sapiens 176-185 12010802-9 2002 This hypothesis was underscored by the finding that the AT III beta-isoform, known to have higher affinity for glycosaminoglycans, is more effective in preventing NF-kappaB transactivation than alpha-AT III. Glycosaminoglycans 111-129 nuclear factor kappa B subunit 1 Homo sapiens 163-172