PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17470431-4	2007	Our data indicate that this interaction is mediated largely through the binding of glycosaminoglycans (specifically chondroitin 6-sulfate) of aggrecan to binding sites in the thrombospondin type 1 motif and spacer domains of ADAMTS-4 to form a complex with an improved binding affinity for TIMP-3 over free ADAMTS-4.	Glycosaminoglycans	83-101	ADAM metallopeptidase with thrombospondin type 1 motif 4	Homo sapiens	225-233	
17470431-4	2007	Our data indicate that this interaction is mediated largely through the binding of glycosaminoglycans (specifically chondroitin 6-sulfate) of aggrecan to binding sites in the thrombospondin type 1 motif and spacer domains of ADAMTS-4 to form a complex with an improved binding affinity for TIMP-3 over free ADAMTS-4.	Glycosaminoglycans	83-101	ADAM metallopeptidase with thrombospondin type 1 motif 4	Homo sapiens	307-315	
10827174-7	2000	Here we demonstrate that the thrombospondin type-1 (TSP-1) motif located within the C terminus of aggrecanase-1 binds to the glycosaminoglycans of aggrecan.	Glycosaminoglycans	125-143	ADAM metallopeptidase with thrombospondin type 1 motif 4	Homo sapiens	98-111	
16507336-2	2006	Accumulating evidence suggests that regulation of the activity of one such aggrecanase, ADAMTS-4 (or Aggrecanase-1), involves post-translational C-terminal processing (truncation) which modulates both glycosaminoglycan (GAG)-binding affinity and enzymatic activity.	Glycosaminoglycans	201-218	ADAM metallopeptidase with thrombospondin type 1 motif 4	Homo sapiens	88-96	
16507336-2	2006	Accumulating evidence suggests that regulation of the activity of one such aggrecanase, ADAMTS-4 (or Aggrecanase-1), involves post-translational C-terminal processing (truncation) which modulates both glycosaminoglycan (GAG)-binding affinity and enzymatic activity.	Glycosaminoglycans	201-218	ADAM metallopeptidase with thrombospondin type 1 motif 4	Homo sapiens	101-114	
16507336-2	2006	Accumulating evidence suggests that regulation of the activity of one such aggrecanase, ADAMTS-4 (or Aggrecanase-1), involves post-translational C-terminal processing (truncation) which modulates both glycosaminoglycan (GAG)-binding affinity and enzymatic activity.	Glycosaminoglycans	220-223	ADAM metallopeptidase with thrombospondin type 1 motif 4	Homo sapiens	88-96	
16507336-2	2006	Accumulating evidence suggests that regulation of the activity of one such aggrecanase, ADAMTS-4 (or Aggrecanase-1), involves post-translational C-terminal processing (truncation) which modulates both glycosaminoglycan (GAG)-binding affinity and enzymatic activity.	Glycosaminoglycans	220-223	ADAM metallopeptidase with thrombospondin type 1 motif 4	Homo sapiens	101-114