PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24911585-4 2014 The three steps which are accompanied with changes in the DNA conformations were detected via 2-aminopurine fluorescence in the process of binding and recognition of damaged oxoG base by hOGG1. 2-Aminopurine 94-107 8-oxoguanine DNA glycosylase Homo sapiens 187-192 28621520-3 2017 Here, we develop a rapid and sensitive fluorescent method for simultaneous detection of human 8-oxoG DNA glycosylase 1 (hOGG1) and uracil DNA glycolase (UDG) using exonuclease-assisted recycling signal amplification in combination with fluorescent bases 2-aminopurine (2-AP) and pyrrolo-dC (P-dC) as the fluorophores. 2-Aminopurine 254-267 8-oxoguanine DNA glycosylase Homo sapiens 120-125 28621520-3 2017 Here, we develop a rapid and sensitive fluorescent method for simultaneous detection of human 8-oxoG DNA glycosylase 1 (hOGG1) and uracil DNA glycolase (UDG) using exonuclease-assisted recycling signal amplification in combination with fluorescent bases 2-aminopurine (2-AP) and pyrrolo-dC (P-dC) as the fluorophores. 2-Aminopurine 269-273 8-oxoguanine DNA glycosylase Homo sapiens 120-125 28621520-6 2017 The presence of hOGG1 and UDG may initiate the signal amplification process by the recycling lambda exonuclease digestion and generates distinct fluorescence signals, with 2-AP indicating the presence of hOGG1 and P-dC indicating the presence of UDG. 2-Aminopurine 172-176 8-oxoguanine DNA glycosylase Homo sapiens 16-21 28621520-6 2017 The presence of hOGG1 and UDG may initiate the signal amplification process by the recycling lambda exonuclease digestion and generates distinct fluorescence signals, with 2-AP indicating the presence of hOGG1 and P-dC indicating the presence of UDG. 2-Aminopurine 172-176 8-oxoguanine DNA glycosylase Homo sapiens 204-209 24096108-3 2014 METHODS: Using pre-steady-state kinetic analysis with Trp and 2-aminopurine fluorescence detection the conformational dynamics of hOGG1 wild-type (WT) and mutants Y203W, Y203A, H270W, F45W, F319W and K249Q as well as DNA-substrates was examined. 2-Aminopurine 62-75 8-oxoguanine DNA glycosylase Homo sapiens 130-135