PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2555543-8 1989 When HeLa cells were infected with R2-2A-2 in the presence of 2-aminopurine, a protein kinase inhibitor, much higher virus titers were produced, cleavage of p220 occurred, and host cell protein synthesis was specifically inhibited. 2-Aminopurine 62-75 eukaryotic translation initiation factor 4 gamma 1 Homo sapiens 157-161 2555543-9 1989 Since phosphorylation of eIF-2 alpha was not inhibited by 2-aminopurine, we propose that 2-aminopurine rescues the ability of R2-2A-2 to induce cleavage of p220 by inhibition of a second as yet unidentified kinase. 2-Aminopurine 89-102 eukaryotic translation initiation factor 4 gamma 1 Homo sapiens 156-160