PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33578126-7	2021	These effects are dependent on RhoA-ROCK signaling and are mediated via increased phosphorylation of eNOS at Threonine (T)-495.	Threonine	109-118	ras homolog family member A	Homo sapiens	31-35	
18000012-6	2008	This increase in GTP-RhoA correlated with an increase in an alternatively spliced form of CRMP-2 (CRMP-2A) and its threonine phosphorylated form.	Threonine	115-124	ras homolog family member A	Homo sapiens	21-25	
22673745-4	2012	Direct participation of residue 43 in GEF-catalyzed exchange was confirmed by the observation that mutation of this position to a threonine reduced GEF-catalyzed nucleotide exchange activity in vitro (Vav2, XPLN, GEFT, Dbl and Dbs) and greatly depressed RhoA and RhoC GTP-loading profiles in cell lysates.	Threonine	130-139	ras homolog family member A	Homo sapiens	254-258	
19829074-6	2009	p27:RhoA binding is facilitated by p27 phosphorylation at threonine 198.	Threonine	58-67	ras homolog family member A	Homo sapiens	4-8	
18829452-7	2008	Here we report on the interactions of RhoA, Rac1, and Cdc42 with mDia1 and an mDia1 mutant (mDia(N)-Thr-Ser-His (TSH)), which based on structural information should mimic mDia2 and -3.	Threonine	100-103	ras homolog family member A	Homo sapiens	38-42	
28509344-10	2017	Thrombin caused the GTP loading and activation of RhoA, leading to the ROCK-mediated phosphorylation of MLCP on threonine 853 (thr853 ), which is known to inhibit phosphatase activity.	Threonine	112-121	ras homolog family member A	Homo sapiens	50-54	
18237278-7	2008	Phosphorylation by Rho kinase of MYPT1 (myosin phosphatase targeting subunit 1) at Thr(696) was masked by phosphorylation of MYPT1 at Ser(695) by PKA derived from IkappaB degradation via RhoA, but unmasked in the presence of PKI (PKA inhibitor) or C3 exoenzyme and in cells expressing IKK2(K44A).	Threonine	83-86	ras homolog family member A	Homo sapiens	187-191	
18211802-6	2008	ERK1/2-mediated Thr(678)-phosphorylation enhanced the guanine nucleotide exchange activity of GEF-H1 toward RhoA.	Threonine	16-19	ras homolog family member A	Homo sapiens	108-112	
15194681-2	2004	Ca(2+) sensitization induced by activation of G protein-coupled receptors acting through RhoA involves phosphorylation of Thr-696 (of the human isoform) of the myosin targeting subunit (MYPT1) of SMPP-1M inhibiting activity.	Threonine	122-125	ras homolog family member A	Homo sapiens	89-93	
17395891-9	2007	Morphine, DAMGO, thrombin, and LPS induced RhoA/ROCK-mediated threonine phosphorylation of S1P(3), which was blocked by MNTX, suggesting S1P(3) transactivation.	Threonine	62-71	ras homolog family member A	Homo sapiens	43-47	
16247472-7	2006	Moreover, ECT2 T412A, but not phosphomimic T412D, displayed a diminished accumulation of GTP-bound RhoA compared with WT ECT2, suggesting that phosphorylation of Thr-412 is critical for the catalytic activity of ECT2.	Threonine	162-165	ras homolog family member A	Homo sapiens	99-103	
12538643-8	2003	The activity of the RhoA inhibitor p190RhoGAP is decreased due to its serine/threonine phosphorylation at this time.	Threonine	77-86	ras homolog family member A	Homo sapiens	20-24	
12748184-3	2003	The binding of HA to MDA-MB-231 cells stimulates p115RhoGEF-mediated RhoA signaling and Rho kinase (ROK) activity, which, in turn, increases serine/threonine phosphorylation of the adaptor protein, Gab-1 (Grb2-associated binder-1).	Threonine	148-157	ras homolog family member A	Homo sapiens	69-73	
11018042-7	2001	These results indicate that ROCK directly phosphorylates threonine 505 and activates LIMK2 downstream of RhoA and that this phosphorylation is essential for LIMK2 to induce actin cytoskeletal reorganization.	Threonine	57-66	ras homolog family member A	Homo sapiens	105-109	
12467978-4	2002	Comparison of the amino acid sequence of the alpha3-helix loop7 regions of the two proteins allowed the identification of the proline 96 and threonine 100 amino acid residues of human RHOA as the most probable determinants of the complementation differences.	Threonine	141-150	ras homolog family member A	Homo sapiens	184-188	
10556088-2	1999	Here, we report that, when NIH3T3 or HeLa cells were transfected with a constitutively active mutant of the small GTPase RhoA (V14RhoA), microvilli were induced and the level of carboxy-terminal threonine-phosphorylated ERM proteins (CPERM) [6] [7] increased approximately 30-fold.	Threonine	195-204	ras homolog family member A	Homo sapiens	121-125