PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29743242-2 2018 Phosphorylation of Thr-186 on the activation loop (T-loop) of cyclin-dependent kinase 9 (CDK9) is essential for its kinase activity and assembly of CDK9 and cyclin T1 (CycT1) to form functional P-TEFb. Threonine 19-22 cyclin T1 Homo sapiens 157-166 18931076-3 2008 Here we report the development of a mutant CycT1 protein, containing three threonine-to-alanine substitutions in the linker region between two of the cyclin boxes, which displays a potent dominant negative effect on HIV transcription. Threonine 75-84 cyclin T1 Homo sapiens 43-48 29743242-2 2018 Phosphorylation of Thr-186 on the activation loop (T-loop) of cyclin-dependent kinase 9 (CDK9) is essential for its kinase activity and assembly of CDK9 and cyclin T1 (CycT1) to form functional P-TEFb. Threonine 19-22 cyclin T1 Homo sapiens 168-173 29743242-6 2018 Arginine triad substitutions that disrupted CDK9/CycT1 assembly accumulated Thr-186-dephosphorylated CDK9 associated with the cytoplasmic Hsp90/Cdc37 chaperone. Threonine 76-79 cyclin T1 Homo sapiens 49-54