PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18387944-8	2008	Evidence is also presented that potassium ions are indispensable for the cross-talk between the nucleotide- and L2-binding sites of PDHK2.	Threonine	112-114	pyruvate dehydrogenase kinase 2	Homo sapiens	132-137	
15364915-3	2004	Membrane-bound Akt is then phosphorylated at two sites for its full activation; Thr-308 in the activation loop of the kinase domain is phosphorylated by 3-phosphoinositide-dependent kinase-1 (PDK1) and Ser-473 in the C-terminal hydrophobic motif by a putative kinase PDK2.	Threonine	80-83	pyruvate dehydrogenase kinase 2	Homo sapiens	267-271	
12682057-5	2003	Immunodepleting cytosolic PDK1 from an in vitro reaction containing plasma membrane and cytosol markedly inhibited insulin-stimulated phosphorylation of Akt at the PDK1 site (Thr-308) but had no effect on phosphorylation at the PDK2 site (Ser-473).	Threonine	175-178	pyruvate dehydrogenase kinase 2	Homo sapiens	228-232	
10874027-4	2000	alpha-Thrombin and thrombopoietin activate PKBalpha via PI-3K and trigger the concurrent phosphorylation of Thr(308) (via PDK1) and Ser(473) (via a not yet identified PDK2).	Threonine	6-9	pyruvate dehydrogenase kinase 2	Homo sapiens	167-171	
11042204-1	2001	Akt activation requires phosphorylation of Thr(308) and Ser(473) by 3-phosphoinositide-dependent kinase-1 and 2 (PDK1 and PDK2), respectively.	Threonine	43-46	pyruvate dehydrogenase kinase 2	Homo sapiens	122-126