PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15876811-0 2005 Cibenzoline attenuates upregulation of Kv1.5 channel gene expression by experimental paroxysmal atrial fibrillation. cifenline 0-11 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 39-44 15876811-4 2005 In rats with rapid atrial pacing, pretreatment with cibenzoline significantly inhibited the increases in Kv1.5 mRNA at 2 hours and immunoreactive protein at 4 hours by 35 +/- 15% and 30 +/- 10%, respectively. cifenline 52-63 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 105-110 15876811-8 2005 In conclusion, in addition to the acute physiological effects, pretreatment with cibenzoline exerted pleiotropic effects of inhibition of Kv1.5 channel upregulation by rapid pacing, implying differences in the cibenzoline effects when administered before and after onset of paroxysmal atrial fibrillation. cifenline 81-92 potassium voltage-gated channel subfamily A member 5 Rattus norvegicus 138-143