PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9588182-6 1998 Site-directed mutagenesis of the glutathione-S-transferase (GST)/PLC-delta 1 fusion protein changing Arg105 to His resulted in a fourfold decrease in the affinity of specific Ins(1,4,5)P3 binding and a reduction in PtdIns(4,5)P2 hydrolysing activity to about 40% of that of the wild-type enzyme. Indium 175-178 glutathione S-transferase kappa 1 Homo sapiens 33-58 9588182-6 1998 Site-directed mutagenesis of the glutathione-S-transferase (GST)/PLC-delta 1 fusion protein changing Arg105 to His resulted in a fourfold decrease in the affinity of specific Ins(1,4,5)P3 binding and a reduction in PtdIns(4,5)P2 hydrolysing activity to about 40% of that of the wild-type enzyme. Indium 175-178 glutathione S-transferase kappa 1 Homo sapiens 60-63