PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28747712-4 2017 We found that cell death induced by 2-oxo-Ado is classical caspase-dependent apoptosis, and requires its sequential intracellular phosphorylation catalysed by adenosine kinase (ADK) and adenylate kinase 2, resulting in intracellular accumulation of 2-oxo-ATP accompanied by accumulation of 2-oxo-Ado in RNA and depletion of ATP. 2-oxo-ado 36-45 adenylate kinase 2 Mus musculus 186-204 28747712-4 2017 We found that cell death induced by 2-oxo-Ado is classical caspase-dependent apoptosis, and requires its sequential intracellular phosphorylation catalysed by adenosine kinase (ADK) and adenylate kinase 2, resulting in intracellular accumulation of 2-oxo-ATP accompanied by accumulation of 2-oxo-Ado in RNA and depletion of ATP. 2-oxo-ado 290-299 adenylate kinase 2 Mus musculus 186-204