PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15608338-7 2005 Exogenous malonate, which feeds into the carboxylation pathway of acetyl-CoA metabolism, chemically complements the morphological and chemical alterations associated with reduced ACL expression, indicating that the observed metabolic alterations are related to the carboxylation pathway of cytosolic acetyl-CoA metabolism. malonic acid 10-18 acetone-cyanohydrin lyase Arabidopsis thaliana 179-182 15608338-8 2005 The observations that limiting the expression of the cytosolic enzyme ACL reduces the accumulation of cytosolic acetyl-CoA-derived metabolites and that these deficiencies can be alleviated by exogenous malonate indicate that ACL is a nonredundant source of cytosolic acetyl-CoA. malonic acid 202-210 acetone-cyanohydrin lyase Arabidopsis thaliana 70-73 15608338-8 2005 The observations that limiting the expression of the cytosolic enzyme ACL reduces the accumulation of cytosolic acetyl-CoA-derived metabolites and that these deficiencies can be alleviated by exogenous malonate indicate that ACL is a nonredundant source of cytosolic acetyl-CoA. malonic acid 202-210 acetone-cyanohydrin lyase Arabidopsis thaliana 225-228