PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34348577-2	2021	The purpose of this work is to probe into the impact of N2O on nerve cell injury through regulating thioredoxin-interacting protein (TXNIP)/the NOD-like receptor domain of pyrin containing 3 (NLRP3) pathway.	Nitrous Oxide	56-59	NLR family, pyrin domain containing 3	Mus musculus	192-197	
34348577-3	2021	The results indicated that, N2O exposure elevated TXNIP/NLRP3 expression in vivo and in vitro, led to declined learning and memory capabilities in mice, reduced apoptosis rate in hippocampal neuron and Nissl bodies, elevated inflammatory factors TNF-alpha, IL-1beta and IL-6 levels, as well as cleaved caspase-3 and Bax expressions, and reduced Bcl-2 expression.	Nitrous Oxide	28-31	NLR family, pyrin domain containing 3	Mus musculus	56-61	
34348577-6	2021	All in all, the results manifested that N2O is available to promote nerve cell inflammation and apoptosis through activating the TXNIP/NLRP3 pathway that can be used as a potential target for N2O-induced nerve damage in the future.	Nitrous Oxide	40-43	NLR family, pyrin domain containing 3	Mus musculus	135-140	
34348577-6	2021	All in all, the results manifested that N2O is available to promote nerve cell inflammation and apoptosis through activating the TXNIP/NLRP3 pathway that can be used as a potential target for N2O-induced nerve damage in the future.	Nitrous Oxide	192-195	NLR family, pyrin domain containing 3	Mus musculus	135-140