PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9632736-2 1998 The p70 S6 kinase is activated by diverse stimuli through a multisite phosphorylation directed at three separate domains as follows: a cluster of (Ser/Thr) Pro sites in an autoinhibitory segment in the noncatalytic carboxyl-terminal tail; Thr-252 in the activation loop of the catalytic domain; and Ser-394 and Thr-412 in a segment immediately carboxyl-terminal to the catalytic domain. Proline 156-159 ubiquitin associated and SH3 domain containing B Homo sapiens 4-7