PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16891373-2 2006 Here we analyze three usages of flexible linkers: 1), intramolecular binding of proline-rich peptides (PRPs) to SH3 domains for kinase regulation; 2), intramolecular binding of PRP for increasing the folding stability of SH3 domains; and 3), covalent linking of PRPs and other ligands for high-affinity bivalent binding. Proline 80-87 caspase recruitment domain family member 14 Homo sapiens 103-106