PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20002521-1 2010 The anti-parkinsonian drug, rasagiline [N-propargyl-1-(R)-aminoindan; Azilect(R)], is a secondary cyclic benzylamine and indane derivative, which provides irreversible, potent monoamine oxidase-B (MAO-B) inhibition and possesses neuroprotective and neurorestorative activities. indan 121-127 monoamine oxidase B Homo sapiens 176-195 20002521-1 2010 The anti-parkinsonian drug, rasagiline [N-propargyl-1-(R)-aminoindan; Azilect(R)], is a secondary cyclic benzylamine and indane derivative, which provides irreversible, potent monoamine oxidase-B (MAO-B) inhibition and possesses neuroprotective and neurorestorative activities. indan 121-127 monoamine oxidase B Homo sapiens 197-202 25820651-2 2015 Based on the structural similarity between alpha-tetralone and 1-indanone, the present study involved synthesis of 34 1-indanone and related indane derivatives as potential inhibitors of recombinant human MAO-A and MAO-B. indan 141-147 monoamine oxidase B Homo sapiens 215-220 34047146-0 2021 New indane derivatives containing 2-hydrazinothiazole as potential acetylcholinesterase and monoamine oxidase-B inhibitors. indan 4-10 monoamine oxidase B Homo sapiens 92-111 34047146-3 2021 In this study, indane ring which are in the structure of anticholinesterase effective molecules and 2-hydrazinothiazole structure whose inhibitory activities reported on monoamine oxidase-B (MAO-B) were combined; 4-(substituted phenyl)-2-[2-(3-phenyl-2,3-dihydro-1H-inden-1-ylidene) hydrazinyl]thiazole derivatives (3a-3i) were synthesized as dual inhibitors. indan 15-21 monoamine oxidase B Homo sapiens 170-189 34047146-3 2021 In this study, indane ring which are in the structure of anticholinesterase effective molecules and 2-hydrazinothiazole structure whose inhibitory activities reported on monoamine oxidase-B (MAO-B) were combined; 4-(substituted phenyl)-2-[2-(3-phenyl-2,3-dihydro-1H-inden-1-ylidene) hydrazinyl]thiazole derivatives (3a-3i) were synthesized as dual inhibitors. indan 15-21 monoamine oxidase B Homo sapiens 191-196 25820651-4 2015 C5-Substituted indanone and indane derivatives are comparatively weaker MAO-B inhibitors. indan 28-34 monoamine oxidase B Homo sapiens 72-77 25820651-5 2015 Although the 1-indanone and indane derivatives are selective inhibitors of the MAO-B isoform, a number of homologues are also potent MAO-A inhibitors, with three homologues possessing IC50 values <0.1 muM. indan 28-34 monoamine oxidase B Homo sapiens 79-84