PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20228170-6 2010 Both T and DHT increased numbers of spermatogonia and spermatocytes in hpg mice, but DHT has no effect on germ cell numbers in hpg.SCARKO and hpg.ARKO mice. Dihydrotestosterone 11-14 gonadotropin releasing hormone 1 Mus musculus 71-74 16837735-5 2006 Castration profoundly reduced Cres mRNA, while replacement with estradiol (E(2)), testosterone (T), or dihydrotestosterone (DHT) further decreased Cres, suggesting negative regulation by GnRH or steroid hormones. Dihydrotestosterone 103-122 gonadotropin releasing hormone 1 Mus musculus 187-191 9492044-0 1998 Regulation of gonadotropin-releasing hormone (GnRH) gene expression by 5alpha-dihydrotestosterone in GnRH-secreting GT1-7 hypothalamic neurons. Dihydrotestosterone 71-97 gonadotropin releasing hormone 1 Mus musculus 14-44 16204337-5 2006 These bone phenotypes of hpg and orchidectomized non-hpg mice were all prevented by replacement doses of T or dihydrotestosterone (DHT), suggesting that these are determined by adult sex steroid hormones. Dihydrotestosterone 110-129 gonadotropin releasing hormone 1 Mus musculus 25-28 16204337-5 2006 These bone phenotypes of hpg and orchidectomized non-hpg mice were all prevented by replacement doses of T or dihydrotestosterone (DHT), suggesting that these are determined by adult sex steroid hormones. Dihydrotestosterone 110-129 gonadotropin releasing hormone 1 Mus musculus 53-56 16204337-5 2006 These bone phenotypes of hpg and orchidectomized non-hpg mice were all prevented by replacement doses of T or dihydrotestosterone (DHT), suggesting that these are determined by adult sex steroid hormones. Dihydrotestosterone 131-134 gonadotropin releasing hormone 1 Mus musculus 25-28 16204337-5 2006 These bone phenotypes of hpg and orchidectomized non-hpg mice were all prevented by replacement doses of T or dihydrotestosterone (DHT), suggesting that these are determined by adult sex steroid hormones. Dihydrotestosterone 131-134 gonadotropin releasing hormone 1 Mus musculus 53-56 15638871-8 2005 RESULTS: We found that AR mRNA levels were significantly down-regulated in the leucocytes of hpg mice that were treated with exogenous testosterone, oestradiol or DHT. Dihydrotestosterone 163-166 gonadotropin releasing hormone 1 Mus musculus 93-96 9492044-0 1998 Regulation of gonadotropin-releasing hormone (GnRH) gene expression by 5alpha-dihydrotestosterone in GnRH-secreting GT1-7 hypothalamic neurons. Dihydrotestosterone 71-97 gonadotropin releasing hormone 1 Mus musculus 46-50 9492044-0 1998 Regulation of gonadotropin-releasing hormone (GnRH) gene expression by 5alpha-dihydrotestosterone in GnRH-secreting GT1-7 hypothalamic neurons. Dihydrotestosterone 71-97 gonadotropin releasing hormone 1 Mus musculus 101-105 9492044-8 1998 Treatment of GT1-7 cells with 1 or 10 nM DHT resulted in approximately 55% reduction in GnRH messenger RNA measured at 24 and 36 h after treatment. Dihydrotestosterone 41-44 gonadotropin releasing hormone 1 Mus musculus 88-92 20739401-0 2010 Progesterone treatment inhibits and dihydrotestosterone (DHT) treatment potentiates voltage-gated calcium currents in gonadotropin-releasing hormone (GnRH) neurons. Dihydrotestosterone 36-55 gonadotropin releasing hormone 1 Mus musculus 118-148 35267218-5 2022 Acute prenatal DHT exposure can also model the hyperandrogenism of PCOS, and this is accompanied by increased LH pulse frequency and increased GABAergic innervation of gonadotrophin-releasing hormone (GnRH) neurons. Dihydrotestosterone 15-18 gonadotropin releasing hormone 1 Mus musculus 168-199 35267218-5 2022 Acute prenatal DHT exposure can also model the hyperandrogenism of PCOS, and this is accompanied by increased LH pulse frequency and increased GABAergic innervation of gonadotrophin-releasing hormone (GnRH) neurons. Dihydrotestosterone 15-18 gonadotropin releasing hormone 1 Mus musculus 201-205 35267218-6 2022 We aimed to determine the impact of chronic exposure of female mice to DHT, which models the hyperandrogenism of PCOS, on pulsatile LH secretion and putative GABAergic input to GnRH neurons. Dihydrotestosterone 71-74 gonadotropin releasing hormone 1 Mus musculus 177-181 339233-2 1977 Administration of the progestins, progesterone and dihydroprogesterone (DHP), and of the hypothalamic decapeptide, LH-RH, 6 hr prior to testing restored receptivity to varying degrees in these E2B + DHT treated mice. Dihydrotestosterone 199-202 gonadotropin releasing hormone 1 Mus musculus 115-120 22623623-10 2012 In hpg testes, DHT treatment stimulated the redistribution of claudin-11 protein toward the basal region of Sertoli cells by Day 2, increased Cldn3 and Cldn11 mRNA expression, then induced the formation of functional TJs containing both proteins by Day 10. Dihydrotestosterone 15-18 gonadotropin releasing hormone 1 Mus musculus 3-6 22623623-11 2012 In hpg+tgFSH testes, TJ protein redistribution was accelerated and functional TJs formed by Day 2 of DHT treatment. Dihydrotestosterone 101-104 gonadotropin releasing hormone 1 Mus musculus 3-6 7588276-6 1995 An in vitro fertilization assay confirmed that both T and DHT induced quantitatively normal fertilizing capacity of the sperm in hpg males. Dihydrotestosterone 58-61 gonadotropin releasing hormone 1 Mus musculus 129-132 19912890-6 1992 Treatment of adult hpg mice with estradiol-17beta, testosterone, or 5alpha-dihydrotestosterone significantly reduced the number of GFAP-positive cells in the periventricular area, but they were still 10-20 times higher in number than in normal mice. Dihydrotestosterone 68-94 gonadotropin releasing hormone 1 Mus musculus 19-22 34503965-3 2021 Female offspring of mice injected with dihydrotestosterone (DHT) on gestational D16-18 exhibit disrupted estrous cyclicity, increased LH and testosterone, and increased GnRH neuron firing rate as adults. Dihydrotestosterone 39-58 gonadotropin releasing hormone 1 Mus musculus 169-173 34503965-3 2021 Female offspring of mice injected with dihydrotestosterone (DHT) on gestational D16-18 exhibit disrupted estrous cyclicity, increased LH and testosterone, and increased GnRH neuron firing rate as adults. Dihydrotestosterone 60-63 gonadotropin releasing hormone 1 Mus musculus 169-173 20739401-0 2010 Progesterone treatment inhibits and dihydrotestosterone (DHT) treatment potentiates voltage-gated calcium currents in gonadotropin-releasing hormone (GnRH) neurons. Dihydrotestosterone 36-55 gonadotropin releasing hormone 1 Mus musculus 150-154 20739401-0 2010 Progesterone treatment inhibits and dihydrotestosterone (DHT) treatment potentiates voltage-gated calcium currents in gonadotropin-releasing hormone (GnRH) neurons. Dihydrotestosterone 57-60 gonadotropin releasing hormone 1 Mus musculus 118-148 20739401-0 2010 Progesterone treatment inhibits and dihydrotestosterone (DHT) treatment potentiates voltage-gated calcium currents in gonadotropin-releasing hormone (GnRH) neurons. Dihydrotestosterone 57-60 gonadotropin releasing hormone 1 Mus musculus 150-154 20410197-1 2010 Both testosterone and its nonaromatizable metabolite dihydrotestosterone (DHT) induce spermatogenesis in gonadotropin-deficient hpg mice. Dihydrotestosterone 53-72 gonadotropin releasing hormone 1 Mus musculus 128-131 20410197-1 2010 Both testosterone and its nonaromatizable metabolite dihydrotestosterone (DHT) induce spermatogenesis in gonadotropin-deficient hpg mice. Dihydrotestosterone 74-77 gonadotropin releasing hormone 1 Mus musculus 128-131