PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16825320-5	2006	We demonstrate that IGFBP-3 expression can be induced by 10 nm of the synthetic androgen R1881 or dihydrotestosterone.	Dihydrotestosterone	98-117	insulin like growth factor binding protein 3	Homo sapiens	20-27	
16368782-0	2006	DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells.	Dihydrotestosterone	0-3	insulin like growth factor binding protein 3	Homo sapiens	86-93	
16368782-9	2006	The effects of DHT on IGF-I, IGFBP-2, and IGFBP-3 were more pronounced in stromal cultures that did not express desmin.	Dihydrotestosterone	15-18	insulin like growth factor binding protein 3	Homo sapiens	42-49	
16368782-5	2006	DHT and T each increased IGF-I (7-fold) and decreased IGFBP-3 (2-fold) mRNA expression and protein secretion in a dose- and time-dependent manner and increased IGFBP-2 (2-fold) mRNA in a dose- and time-dependent manner.	Dihydrotestosterone	0-3	insulin like growth factor binding protein 3	Homo sapiens	54-61	
10875240-0	2000	Insulin-like growth factor binding protein-3 is regulated by dihydrotestosterone and stimulates deoxyribonucleic acid synthesis and cell proliferation in LNCaP prostate carcinoma cells.	Dihydrotestosterone	61-80	insulin like growth factor binding protein 3	Homo sapiens	0-44	
10875240-4	2000	Cell-associated IGFBP-3, and immunoreactive IGFBP-3 species of 20 kDa and 30 kDa were also increased in response to vitamin D plus DHT.	Dihydrotestosterone	131-134	insulin like growth factor binding protein 3	Homo sapiens	16-23	
10875240-4	2000	Cell-associated IGFBP-3, and immunoreactive IGFBP-3 species of 20 kDa and 30 kDa were also increased in response to vitamin D plus DHT.	Dihydrotestosterone	131-134	insulin like growth factor binding protein 3	Homo sapiens	44-51	
10875240-5	2000	A combination of vitamin D and DHT increased DNA synthesis in LNCaP cells 3-fold, and this was at least partly mediated by endogenous IGFBP-3 because anti-IGFBP-3 IgG, but not nonimmune serum IgG, reduced the stimulatory effect of vitamin D and DHT from 293 +/- 11.6% to 161 +/- 30.7% of control levels (P < 0.0001).	Dihydrotestosterone	31-34	insulin like growth factor binding protein 3	Homo sapiens	134-141	
10875240-5	2000	A combination of vitamin D and DHT increased DNA synthesis in LNCaP cells 3-fold, and this was at least partly mediated by endogenous IGFBP-3 because anti-IGFBP-3 IgG, but not nonimmune serum IgG, reduced the stimulatory effect of vitamin D and DHT from 293 +/- 11.6% to 161 +/- 30.7% of control levels (P < 0.0001).	Dihydrotestosterone	31-34	insulin like growth factor binding protein 3	Homo sapiens	155-162	
10875240-5	2000	A combination of vitamin D and DHT increased DNA synthesis in LNCaP cells 3-fold, and this was at least partly mediated by endogenous IGFBP-3 because anti-IGFBP-3 IgG, but not nonimmune serum IgG, reduced the stimulatory effect of vitamin D and DHT from 293 +/- 11.6% to 161 +/- 30.7% of control levels (P < 0.0001).	Dihydrotestosterone	245-248	insulin like growth factor binding protein 3	Homo sapiens	134-141	
10875240-6	2000	Basal and DHT plus vitamin D-stimulated thymidine incorporation was significantly increased by 50 ng/ml human plasma-derived purified IGFBP-3.	Dihydrotestosterone	10-13	insulin like growth factor binding protein 3	Homo sapiens	134-141	
10875240-2	2000	Confluent monolayers of cells secreted approximately 0.7 ng/ml IGFBP-3 over 24 h. Dihydrotestosterone (DHT, 10 nM) and 1,25-dihydroxyvitamin D3 (vitamin D, 10 nM) increased IGFBP-3 in media to 149 +/- 15% and 206 +/- 18% of control, respectively, when added separately, and to 453 +/- 28% of control when used in combination.	Dihydrotestosterone	82-101	insulin like growth factor binding protein 3	Homo sapiens	63-70	
10875240-3	2000	IGFBP-2, secreted at approximately 25-fold higher concentrations than IGFBP-3, was increased 50% by 10 nM DHT, but there was no effect of vitamin D on IGFBP-2 production in the absence or presence of DHT.	Dihydrotestosterone	106-109	insulin like growth factor binding protein 3	Homo sapiens	70-77