PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12948398-2 2003 The high basal activity of mCAR can be modulated by inhibitory steroids related to androstenol and by activating xenobiotic chemicals such as 1,4-bis-[2-(3,5-dichloropyridyloxy)]benzene and chlorpromazine. Androstenols 83-94 coxsackie virus and adenovirus receptor Mus musculus 27-31 14561088-2 2003 Uniquely among nuclear receptors, mouse CAR (mCAR) can be suppressed by androstenol and activated by structurally diverse drugs, pesticides, and environmental pollutants. Androstenols 72-83 coxsackie virus and adenovirus receptor Mus musculus 45-49 14561088-6 2003 Analysis of chimeric and mutant mCAR constructs suggested that androstenol sensitivity is controlled by residues between amino acids 201-263 (helices 5-7) and it does not depend on the residue 350 within helix 12, as previously suggested. Androstenols 63-74 coxsackie virus and adenovirus receptor Mus musculus 32-36 12869636-8 2003 Androstenol repressed the mCAR-mediated constitutive activation of the CYP2C19 promoter in HepG2 cells, whereas the potent mCAR ligand 1,4-bis[2-3,5-dichloropyridyloxyl)] benzene derepressed this response. Androstenols 0-11 coxsackie virus and adenovirus receptor Mus musculus 26-30