PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31751559-9	2020	Injection of cerulein for 2 days induced progressive pancreatitis in T7K24R mice, but not in control mice, with typical features of chronic pancreatitis CONCLUSIONS: Introduction of a mutation into mice that is analogous to the p.K23R mutation in PRSS1 increases pancreatic activation of trypsinogen during secretagogue-induced pancreatitis.	Ceruletide	13-21	protease, serine 1 (trypsin 1)	Mus musculus	247-252	
32724472-5	2020	Humanized PRSS1 transgenic mice were treated with caerulein to mimic the SAP development, which was crossed to an ATF6 knockout mouse line, and pancreatic tissues from the resulting pups were screened by proteomics.	Ceruletide	50-59	protease, serine 1 (trypsin 1)	Mus musculus	10-15	
31419436-13	2020	Increased expression of PRSS1 or PRSS1R122H increased focal damage in pancreatic tissues and increased the severity of acute pancreatitis after caerulein injection.	Ceruletide	144-153	protease, serine 1 (trypsin 1)	Mus musculus	24-29	
31506423-6	2019	A humanized PRSS1 transgenic mouse was established and treated with caerulein to mimic the development of CP, as evidenced by pathogenic alterations, collagen deposition, and increased expression of the inflammatory factors IL-6, IL-1beta, and TNF-alpha.	Ceruletide	68-77	protease, serine 1 (trypsin 1)	Mus musculus	12-17