PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34882521-8 2022 Circ_0073748 was upregulated and miR-132-3p was downregulated in AP patients" plasma and human pancreatic ductal HPDE6-C7 cells with caerulein induction. Ceruletide 133-142 microRNA 1323 Homo sapiens 33-43 34882521-9 2022 Interfering circ_0073748 and reinforcing miR-132-3p improved cell viability, EdU incorporation, and superoxide dismutase (SOD) activity of caerulein-treated HPDE6-C7 cells but suppressed malonaldehyde (MDA), IL-6 and TNF-alpha levels and apoptosis rate. Ceruletide 139-148 microRNA 1323 Homo sapiens 41-51 34882521-10 2022 Moreover, TRAF3 downregulation was allied with circ_0073748 silencing and miR-132-3p overexpression in caerulein-induced HPDE6-C7 cells. Ceruletide 103-112 microRNA 1323 Homo sapiens 74-84 34882521-12 2022 Notably, circ_0073748 blockage could suppress expressions of phosphorylated P65 (p-P65) and p-IkappaB in caerulein-induced HPDE6-C7 cells by promoting miR-132-3p and inhibiting TRAF3. Ceruletide 105-114 microRNA 1323 Homo sapiens 151-161 34882521-13 2022 Silencing circ_0073748 and upregulating miR-132-3p could alleviate caerulein-induced HPDE6-C7 injury and inactivate canonical NF-kappaB signal by inhibiting TRAF3. Ceruletide 67-76 microRNA 1323 Homo sapiens 40-50 34882521-14 2022 Circ_0073748/miR-132-3p/TRAF3 ceRNA pathway might be one underlying mechanism and therapeutic target of caerulein-induced AP. Ceruletide 104-113 microRNA 1323 Homo sapiens 13-23