PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8394964-1	1993	The purpose of this study was to examine the effects of the kappa opioid receptor agonist U-50,488 and antagonist nor-binaltorphimine (NOR-BNI) on the secretion of prolactin and alpha-melanocyte-stimulating hormone (alpha MSH) in male and female rats.	norbinaltorphimine	114-133	proopiomelanocortin	Rattus norvegicus	178-214	
8394964-1	1993	The purpose of this study was to examine the effects of the kappa opioid receptor agonist U-50,488 and antagonist nor-binaltorphimine (NOR-BNI) on the secretion of prolactin and alpha-melanocyte-stimulating hormone (alpha MSH) in male and female rats.	norbinaltorphimine	135-142	proopiomelanocortin	Rattus norvegicus	178-214	
8394964-3	1993	U-50,488 also increased and NOR-BNI decreased plasma concentrations of alpha MSH; similar effects were observed in both male and female rats.	norbinaltorphimine	28-35	proopiomelanocortin	Rattus norvegicus	71-80	
2177159-5	1990	The effects of U-50488 on plasma alpha-MSH concentrations and intermediate-lobe DOPA accumulation were blocked by pretreatment with the selective kappa-opioid receptor antagonist nor-binaltorphimine.	norbinaltorphimine	179-198	proopiomelanocortin	Rattus norvegicus	33-42	
1327383-10	1992	Nor-binaltorphimine (Nor-BNI) largely reversed the analgesic effects of alpha-MSH, [N1(4), D-Phe7]alpha-MSH, Lys-Pro-Val and Lys-D-Pro-Val indicating that kappa-opioid receptors mediated the analgesic activity of these peptides.	norbinaltorphimine	0-19	proopiomelanocortin	Rattus norvegicus	72-81	
1327383-10	1992	Nor-binaltorphimine (Nor-BNI) largely reversed the analgesic effects of alpha-MSH, [N1(4), D-Phe7]alpha-MSH, Lys-Pro-Val and Lys-D-Pro-Val indicating that kappa-opioid receptors mediated the analgesic activity of these peptides.	norbinaltorphimine	0-19	proopiomelanocortin	Rattus norvegicus	98-107	
1327383-10	1992	Nor-binaltorphimine (Nor-BNI) largely reversed the analgesic effects of alpha-MSH, [N1(4), D-Phe7]alpha-MSH, Lys-Pro-Val and Lys-D-Pro-Val indicating that kappa-opioid receptors mediated the analgesic activity of these peptides.	norbinaltorphimine	21-28	proopiomelanocortin	Rattus norvegicus	72-81	
1327383-10	1992	Nor-binaltorphimine (Nor-BNI) largely reversed the analgesic effects of alpha-MSH, [N1(4), D-Phe7]alpha-MSH, Lys-Pro-Val and Lys-D-Pro-Val indicating that kappa-opioid receptors mediated the analgesic activity of these peptides.	norbinaltorphimine	21-28	proopiomelanocortin	Rattus norvegicus	98-107