PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25861786-1 2015 Several chemically diverse pruritogens, including bombesin, compound 48/80, norbinaltorphimine, and 5"-GNTI, cause rodents to scratch excessively in a stable, uniform manner and consequently provide convenient animal models of itch against which potential antipruritics may be evaluated, structure-activity relationships established, and the nature of spontaneous, repetitive behavior itself analyzed. norbinaltorphimine 76-94 itchy E3 ubiquitin protein ligase Homo sapiens 227-231