PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24570112-0 2014 Piracetam ameliorated oxygen and glucose deprivation-induced injury in rat cortical neurons via inhibition of oxidative stress, excitatory amino acids release and P53/Bax. Piracetam 0-9 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 163-166 24570112-1 2014 Our previous work has demonstrated that piracetam inhibited the decrease in amino acid content induced by chronic hypoperfusion, ameliorated the dysfunction of learning and memory in a hypoperfusion rat model, down-regulated P53, and BAX protein, facilitated the synaptic plasticity, and may be helpful in the treatment of vascular dementia. Piracetam 40-49 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 225-228 24570112-6 2014 Furthermore, Western blot study demonstrated that piracetam attenuated the increased expression of P53 and BAX protein in OGD cells. Piracetam 50-59 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 99-102 24570112-7 2014 These observations demonstrated that piracetam reduced OGD-induced neuronal damage by inhibiting the oxidative stress and decreasing excitatory amino acids release and lowering P53/Bax protein expression in OGD cells. Piracetam 37-46 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 177-180