PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28545313-8	2017	RESULTS: APAP-induced oxidative stress in liver by a significant increase in the level of MDA (7.6 +- 0.21 nmol/mg) as well as a decrease in the contents of TAC (1.75 +- 0.14 mumol/g), GSH (1.9 +- 0.22 mumol/g) and GST) 3.2 +- 0.28 U/mg).	Acetaminophen	9-13	hematopoietic prostaglandin D synthase	Rattus norvegicus	215-218	
28510973-4	2014	Whereas, GSH level and GST activity were decreased significantly after acetaminophen treatment.	Acetaminophen	71-84	hematopoietic prostaglandin D synthase	Rattus norvegicus	23-26	
15707775-5	2005	Activity of the antioxidant enzymes in the liver inhibited by APAP was increased in the majority of groups after administration of the substances tested: catalase (CAT) by 55%, glutathione peroxidase (GPx) by 50%, glutathione reductase (GR) by 35% and glutathione S-transferase (GST) by 60%.	Acetaminophen	62-66	hematopoietic prostaglandin D synthase	Rattus norvegicus	252-277	
21569833-8	2011	Incubation with NADPH and acetaminophen elicited lipid peroxidation and decreased thiol content and glutathione-S-transferase (GST) activity.	Acetaminophen	26-39	hematopoietic prostaglandin D synthase	Rattus norvegicus	100-125	
21569833-8	2011	Incubation with NADPH and acetaminophen elicited lipid peroxidation and decreased thiol content and glutathione-S-transferase (GST) activity.	Acetaminophen	26-39	hematopoietic prostaglandin D synthase	Rattus norvegicus	127-130	
20804811-3	2010	Paracetamol caused an elevation in thiobarbituric acid-reactive substances (TBARS) paralleled with significant decline in glutathione peroxidase, glutathione S-transferase, superoxide dismutase and catalase activities (in plasma, brain, lung, heart, liver, kidney and testes) and glutathione content (in lung, liver and kidney).	Acetaminophen	0-11	hematopoietic prostaglandin D synthase	Rattus norvegicus	146-171	
19782400-9	2010	Arsenic or acetaminophen given alone depleted GSH and decreased the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glutathione-S-transferase and these effects remained mostly unaffected after co-exposure.	Acetaminophen	11-24	hematopoietic prostaglandin D synthase	Rattus norvegicus	164-189	
18166521-4	2008	Acetaminophen induced a significant rise in aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP), total bilirubin, gamma glutamate transpeptidase (GGTP), lipid peroxidase (LPO) with a reduction of total protein, superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx) and glutathione S-transferase (GST).	Acetaminophen	0-13	hematopoietic prostaglandin D synthase	Rattus norvegicus	325-350	
18166521-4	2008	Acetaminophen induced a significant rise in aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP), total bilirubin, gamma glutamate transpeptidase (GGTP), lipid peroxidase (LPO) with a reduction of total protein, superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx) and glutathione S-transferase (GST).	Acetaminophen	0-13	hematopoietic prostaglandin D synthase	Rattus norvegicus	352-355	
15875720-3	2005	Paracetamol administration significantly reduced hepatic glycogen, glutathione (GSH), glutathione-S-transferase (GST), glutathione peroxidase (GPX) and glutathione reductase (GSH-R).	Acetaminophen	0-11	hematopoietic prostaglandin D synthase	Rattus norvegicus	86-111	
15875720-3	2005	Paracetamol administration significantly reduced hepatic glycogen, glutathione (GSH), glutathione-S-transferase (GST), glutathione peroxidase (GPX) and glutathione reductase (GSH-R).	Acetaminophen	0-11	hematopoietic prostaglandin D synthase	Rattus norvegicus	113-116	
15707775-5	2005	Activity of the antioxidant enzymes in the liver inhibited by APAP was increased in the majority of groups after administration of the substances tested: catalase (CAT) by 55%, glutathione peroxidase (GPx) by 50%, glutathione reductase (GR) by 35% and glutathione S-transferase (GST) by 60%.	Acetaminophen	62-66	hematopoietic prostaglandin D synthase	Rattus norvegicus	279-282