PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30021675-0	2019	Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury: possible involvement of ER stress and S6K1 activation.	Acetaminophen	44-57	sirtuin 2	Mus musculus	16-24	
30021675-4	2019	Moreover, the ablation of Sirt2 attenuates APAP-induced liver injuries, such as oxidative stress and mitochondrial damage in hepatocytes.	Acetaminophen	43-47	sirtuin 2	Mus musculus	26-31	
30021675-5	2019	We found that Sirt2 deficiency alleviates the APAP-mediated endoplasmic reticulum (ER) stress and phosphorylation of the p70 ribosomal S6 kinase 1 (S6K1).	Acetaminophen	46-50	sirtuin 2	Mus musculus	14-19	
30021675-7	2019	This study elucidates the molecular mechanisms underlying the protective role of Sirt2 inactivation in APAP-induced liver injuries.	Acetaminophen	103-107	sirtuin 2	Mus musculus	81-86	
29449643-13	2018	Interestingly, SIRT2-KO mice were resistant to acetaminophen-induced liver toxicity.	Acetaminophen	47-60	sirtuin 2	Mus musculus	15-20	
29449643-14	2018	SIRT2-KO mice show lower cell death, minimal degenerative changes, improved liver function and survival following acetaminophen treatment.	Acetaminophen	114-127	sirtuin 2	Mus musculus	0-5