PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20847298-0	2010	Lipopolysaccharide binding protein inhibitory peptide protects against acetaminophen-induced hepatotoxicity.	Acetaminophen	71-84	lipopolysaccharide binding protein	Mus musculus	0-34	
20847298-2	2010	Our previous work demonstrated that LPS binding protein (LBP) knockout mice are protected from APAP-induced hepatotoxicity.	Acetaminophen	95-99	lipopolysaccharide binding protein	Mus musculus	36-55	
20847298-2	2010	Our previous work demonstrated that LPS binding protein (LBP) knockout mice are protected from APAP-induced hepatotoxicity.	Acetaminophen	95-99	lipopolysaccharide binding protein	Mus musculus	57-60	
20847298-12	2010	Our results suggest that blocking LBP-LPS interactions is a potential therapeutic avenue for the treatment of APAP-induced liver injury.	Acetaminophen	110-114	lipopolysaccharide binding protein	Mus musculus	34-37	
15619225-0	2005	Lipopolysaccharide-binding protein modulates acetaminophen-induced liver injury in mice.	Acetaminophen	45-58	lipopolysaccharide binding protein	Mus musculus	0-34	
15619225-4	2005	We found that LBP KO mice were protected from acetaminophen-induced hepatotoxicity.	Acetaminophen	46-59	lipopolysaccharide binding protein	Mus musculus	14-17	
15619225-5	2005	At 350 mg/kg of acetaminophen, LBP KO mice had significantly less liver injury and necrosis than wild-type mice.	Acetaminophen	16-29	lipopolysaccharide binding protein	Mus musculus	31-34	
15619225-6	2005	Repletion studies in LBP KO mice using an LBP-adenoviral construct resulted in significantly more hepatic injury and necrosis after acetaminophen exposure compared with mice receiving the control adenoviral construct.	Acetaminophen	132-145	lipopolysaccharide binding protein	Mus musculus	21-24	
15619225-6	2005	Repletion studies in LBP KO mice using an LBP-adenoviral construct resulted in significantly more hepatic injury and necrosis after acetaminophen exposure compared with mice receiving the control adenoviral construct.	Acetaminophen	132-145	lipopolysaccharide binding protein	Mus musculus	42-45	
15619225-7	2005	In conclusion, LBP KO mice are protected from toxicity with a decrease in hepatic necrosis following acetaminophen challenge.	Acetaminophen	101-114	lipopolysaccharide binding protein	Mus musculus	15-18	
15619225-8	2005	This suggests a novel role for LBP in modulating acetaminophen-induced liver injury.	Acetaminophen	49-62	lipopolysaccharide binding protein	Mus musculus	31-34	
22278340-3	2012	METHODS: Serum and hepatic LBP were measured in acute APAP-induced liver injury in mice.	Acetaminophen	54-58	lipopolysaccharide binding protein	Mus musculus	27-30	
22278340-5	2012	RESULTS: Interestingly, contrary to other diseases, serum and hepatic LBP levels decreased significantly in mice within 24 h after being subjected to APAP-induced injury compared to the control (1.6 +- 0.1 vs. 3.5 +- 1.6 mug/ml, respectively; P < 0.05).	Acetaminophen	150-154	lipopolysaccharide binding protein	Mus musculus	70-73