PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15964796-5 2005 To investigate the physiological functional outcome of these C-terminal modifications in regulating p53 stability and activity, we introduced missense mutations (lysine to arginine) at the six lysine residues (K6R) into the endogenous p53 gene in mouse embryonic stem (ES) cells. k6r 210-213 transformation related protein 53, pseudogene Mus musculus 235-238