PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27966348-3	2017	The first step is coordination of the pyridine-AlMe3 adduct with the active species Ni(0)(NHC)(C2H2) 1 in an eta2-fashion to form an intermediate Int1.	pyridine	38-46	Wnt family member 1	Homo sapiens	146-150	
27966348-4	2017	After the isomerization of Int1, the oxidative addition of the C-H bond of pyridine across the nickel-acetylene moiety occurs via a transition state TS2 to form a Ni(II)(NHC) pyridyl vinyl intermediate Int3.	pyridine	75-83	Wnt family member 1	Homo sapiens	27-31	
22940872-1	2013	Density functional theory (DFT) calculations at B3LYP/6-31 G (d,p) and B3LYP/6-311+G(d,p) levels for the substituted pyridine-catalyzed isomerization of monomethyl maleate revealed that isomerization proceeds via four steps, with the rate-limiting step being proton transfer from the substituted pyridinium ion to the C=C double bond in INT1.	pyridine	117-125	Wnt family member 1	Homo sapiens	337-341