PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10995066-1 2000 Synthesis of weakly basic thrombin inhibitors incorporating pyridinium-sulfanilylaminoguanidine moieties. pyridine 60-70 coagulation factor II, thrombin Homo sapiens 26-34 18019535-0 2007 Design, synthesis and biological evaluation of thrombin inhibitors based on a pyridine scaffold. pyridine 78-86 coagulation factor II, thrombin Homo sapiens 47-55 18019535-2 2007 A Grignard exchange reaction was used to introduce various benzoyl substituents in position 4 of the pyridine ring, where they serve as P3 residues in binding to thrombin. pyridine 101-109 coagulation factor II, thrombin Homo sapiens 162-170 10889318-1 1999 Synthesis of non-basic thrombin inhibitors incorporating pyridinium-sulfanilylguanidine moieties at the P1 site. pyridine 57-67 coagulation factor II, thrombin Homo sapiens 23-31