PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21605206-2 2011 Here, we analyzed how duplicated genes encoding quinolinate phosphoribosyltransferase (QPT), an enzyme involved in the synthesis of nicotinamide adenine dinucleotide (NAD) and the pyridine moiety of nicotine, are regulated by the jasmonate-responsive transcriptional factor ERF189 that functions critically for nicotine biosynthesis in tobacco (Nicotiana tabacum). pyridine 180-188 nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic-like Nicotiana tabacum 48-85 21605206-2 2011 Here, we analyzed how duplicated genes encoding quinolinate phosphoribosyltransferase (QPT), an enzyme involved in the synthesis of nicotinamide adenine dinucleotide (NAD) and the pyridine moiety of nicotine, are regulated by the jasmonate-responsive transcriptional factor ERF189 that functions critically for nicotine biosynthesis in tobacco (Nicotiana tabacum). pyridine 180-188 nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic-like Nicotiana tabacum 87-90 21605206-7 2011 These results indicate that one copy of the duplicated QPT genes was recruited to a tobacco alkaloid regulon by evolving multiple target cis-regulatory elements of ERF189 in its promoter, to cope with an increased metabolic demand for pyridine precursors during active alkaloid biosynthesis. pyridine 235-243 nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic-like Nicotiana tabacum 55-58