PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9836623-8 1998 SAR studies revealed that the pyridine nitrogen atom and the nature and the position of the substituents on the pyridine ring were critically involved in the ability of the compounds to recognize and activate 5-HT1A receptors. pyridine 30-38 5-hydroxytryptamine receptor 1A Homo sapiens 209-215 20580787-1 2010 A novel pyridine derivative, 8-{4-[(6-methoxy-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-3-ylmethyl)-amino]-butyl}-8-aza-spiro[4.5]decane-7,9-dione hydrochloride, termed JB-788, was designed to selectively target 5-HT(1A) receptors. pyridine 8-16 5-hydroxytryptamine receptor 1A Homo sapiens 210-217 9836623-8 1998 SAR studies revealed that the pyridine nitrogen atom and the nature and the position of the substituents on the pyridine ring were critically involved in the ability of the compounds to recognize and activate 5-HT1A receptors. pyridine 112-120 5-hydroxytryptamine receptor 1A Homo sapiens 209-215 7473547-11 1995 The CAR activities of pyrroles 6 and 12, thiophene 40, furans 44-47, isoxazolines 49 and 50, and pyridine 54 coupled with their weak or nonexistent D2 binding and strong 5-HT1A binding suggest that they may be acting via a nondopaminergic mechanism or that dopaminergic active metabolites are responsible. pyridine 97-105 5-hydroxytryptamine receptor 1A Homo sapiens 170-176