PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23136724-0	2012	The history of cholinesterase reactivation: hydroxylamine and pyridinium aldoximes.	pyridine	62-72	butyrylcholinesterase	Homo sapiens	15-29	
19456290-2	2009	Pyridinium aldoximes are medically used to reactivate the cholinesterase enzymes inhibited by organophosphates.	pyridine	0-10	butyrylcholinesterase	Homo sapiens	58-72	
11831902-5	2002	Three compounds, 9 (a tertiary pyridine), 10 (a quaternary pyridine), and 12 (a tertiary tetrahydropyridine), were found to be effective inhibitors of both BChE and AChE.	pyridine	31-39	butyrylcholinesterase	Homo sapiens	156-160	
29031067-1	2017	A new series of pyridine derivatives with carbamic or amidic function has been designed and synthesized to act as cholinesterase inhibitors.	pyridine	16-24	butyrylcholinesterase	Homo sapiens	114-128	
24599312-2	2014	These compounds show an ability to reactivate VX-inhibited BChE largely superior to those of known pyridinium aldoximes.	pyridine	99-109	butyrylcholinesterase	Homo sapiens	59-63	
26827140-3	2016	Pyridine-containing compounds were more selective toward BChE; compounds with the para-OMe substituent in one of the two dibenzyl fragments were more selective toward CaE.	pyridine	0-8	butyrylcholinesterase	Homo sapiens	57-61	
27581632-1	2016	A series of pyridinium salts bearing alkylphenyl groups at 1 position and hydrazone structure at 4 position of the pyridinium ring were synthesized and evaluated for the inhibition of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes.	pyridine	12-22	butyrylcholinesterase	Homo sapiens	221-242	
27581632-1	2016	A series of pyridinium salts bearing alkylphenyl groups at 1 position and hydrazone structure at 4 position of the pyridinium ring were synthesized and evaluated for the inhibition of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes.	pyridine	12-22	butyrylcholinesterase	Homo sapiens	244-249	
25291712-3	2015	Pyridinium aldoximes have antidotal effects against poisoning with cholinesterase inhibitors, a frequent problem affecting people working with organophosphate-based insecticides and pesticides.	pyridine	0-10	butyrylcholinesterase	Homo sapiens	67-81	
24220173-0	2013	Preparation, in vitro evaluation and molecular modelling of pyridinium-quinolinium/isoquinolinium non-symmetrical bisquaternary cholinesterase inhibitors.	pyridine	60-70	butyrylcholinesterase	Homo sapiens	128-142