PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3746811-4 1986 The 4-alkyl compounds, in contrast, formed a pyridine derivative in which a hydrogen atom was present at the 4-position and the alkyl group was lost; these compounds also inactivated cytochrome P-450 and caused the loss of nifedipine oxidase activity after enzymatic oxidation. pyridine 45-53 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 194-199 15081432-3 2004 Based on their common pyridine functionality, we hypothesized that these two molecules could inhibit human P450 enzymes. pyridine 22-30 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 107-111