PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25659771-1 2015 A series of pyridine derivatives in the C-region of N-((6-trifluoromethyl-pyridin-3-yl)methyl) 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides were investigated as hTRPV1 antagonists. pyridine 12-20 transient receptor potential cation channel subfamily V member 1 Homo sapiens 169-175 23685943-5 2013 Docking analysis of 53S using our hTRPV1 homology model indicated that the A- and B-region 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamide made important hydrophobic and hydrogen bonding interactions with Tyr511 and that the C-region 6-trifluoromethyl and 2-benzyloxy groups of pyridine occupied the two hydrophobic binding pockets, respectively. pyridine 282-290 transient receptor potential cation channel subfamily V member 1 Homo sapiens 34-40