PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30103189-0 2018 Pyridine bioisosteres of potent GluN2B subunit containing NMDA receptor antagonists with benzo[7]annulene scaffold. pyridine 0-8 glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens 32-38 30103189-7 2018 The >100-fold reduced GluN2B affinity of pyridines 11b and 11c compared to the GluN2B affinity of the corresponding chloro- and nitrobenzene derivatives 3d and 3e indicates that the pyridine ring is not tolerated as bioisosteric replacement of the chloro- or nitrobenzene ring in this type of compounds. pyridine 44-52 glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens 25-31