PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31473473-0	2019	Dual VEGFR-2/PIM-1 kinase inhibition towards surmounting the resistance to antiangiogenic agents via hybrid pyridine and thienopyridine-based scaffolds: Design, synthesis and biological evaluation.	pyridine	108-116	kinase insert domain receptor	Homo sapiens	5-12	
33798847-0	2021	Discovery of pyridine- sulfonamide hybrids as a new scaffold for the development of potential VEGFR-2 inhibitors and apoptosis inducers.	pyridine	13-21	kinase insert domain receptor	Homo sapiens	94-101	
33948983-0	2021	Pyridine-derived VEGFR-2 inhibitors: Rational design, synthesis, anticancer evaluations, in silico ADMET profile, and molecular docking.	pyridine	0-8	kinase insert domain receptor	Homo sapiens	17-24	
32889383-0	2020	Selective VEGFR-2 inhibitors: Synthesis of pyridine derivatives, cytotoxicity and apoptosis induction profiling.	pyridine	43-51	kinase insert domain receptor	Homo sapiens	10-17	
34745424-6	2021	In order to discover novel VEGFR-2 TK inhibitors, we have designed and synthesized three new series of pyridine-containing compounds.	pyridine	103-111	kinase insert domain receptor	Homo sapiens	27-34	
33948983-1	2021	Novel pyridine-derived compounds (5-19) were designed and synthesized, and their anticancer activities were evaluated against HepG2 and MCF-7 cells, targeting the VEGFR-2 enzyme.	pyridine	6-14	kinase insert domain receptor	Homo sapiens	163-170	
30503935-6	2019	Therefore, 1,2,3-triazole could serve as a promising DFG binding group for multi-target inhibitors of VEGFR-2, Tie-2 and EphB4 bearing pyridine as hinge binding group.	pyridine	135-143	kinase insert domain receptor	Homo sapiens	102-109	
25982075-8	2015	SAR study suggested that incorporation of 3-trifluoromethyl and methylamine carbonyl on terminal pyridine could improve VEGFR-2 inhibitory activity.	pyridine	97-105	kinase insert domain receptor	Homo sapiens	120-127