PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28150530-8 2018 The binding affinities of these seven compounds on AKT1 and AKT3 isoforms were mainly determined by hydrophobic contributions between the aromatic portion at position 4 of the pyridine ring with residues Phe236/234, Phe237/235, Phe438/435, and Phe442/439 in the ATP binding pocket. pyridine 176-184 AKT serine/threonine kinase 3 Homo sapiens 60-64