PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11899248-6	2001	Inhibitor binding to fXa was increased by the introduction of a hydroxyl group on the proximal phenylamidine ring and by the introduction of fluorine atoms at C-3 and C-5 of the pyridine ring.	pyridine	178-186	coagulation factor X	Homo sapiens	21-24	
15465335-6	2004	From observations of the SAR and modeling studies, we suggested the possibilities that the formation of hydrogen bond with the oxide anion in the "cation hole" and the affinity of cationic pyridine ring to S4 subsite were responsible for increase in anti-fXa activity.	pyridine	189-197	coagulation factor X	Homo sapiens	255-258	
9618463-5	1998	The biphenylamidine of FX-2212a occupies the S1-pocket, and the pyridine ring makes hydrophobic interactions with the factor Xa aryl-binding site.	pyridine	64-72	coagulation factor X	Homo sapiens	118-127