PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21434856-3 2011 It is now commonly held that loss of Sod2 expression is likely an early event in tumor progression allowing for further propagation of the tumorigenic phenotype resulting from steady state increases in free radical production. Free Radicals 202-214 superoxide dismutase 2 Homo sapiens 37-41 25497738-2 2015 Glutathione peroxidase (GPx) is one of the first endogenous antioxidant defense enzymes, and it works cooperatively with superoxide dismutase (SOD) and catalase (CAT) to detoxify free radicals from the cellular environment. Free Radicals 179-192 superoxide dismutase 2 Homo sapiens 143-146 27141263-3 2016 Superoxide dismutase 2 (SOD2) is one of the major antioxidant defense systems against free radicals. Free Radicals 86-99 superoxide dismutase 2 Homo sapiens 0-22 27141263-3 2016 Superoxide dismutase 2 (SOD2) is one of the major antioxidant defense systems against free radicals. Free Radicals 86-99 superoxide dismutase 2 Homo sapiens 24-28 23243068-1 2013 Manganese superoxide dismutase (MnSOD), a major antioxidant enzyme within the mitochondria, is responsible for the detoxification of free radicals generated by cellular metabolism and environmental/therapeutic irradiation. Free Radicals 133-146 superoxide dismutase 2 Homo sapiens 0-30 23243068-1 2013 Manganese superoxide dismutase (MnSOD), a major antioxidant enzyme within the mitochondria, is responsible for the detoxification of free radicals generated by cellular metabolism and environmental/therapeutic irradiation. Free Radicals 133-146 superoxide dismutase 2 Homo sapiens 32-37 16141349-5 2006 Essentially all of these events were reversed by free radical scavengers such as the manganese superoxide dismutase (MnSOD) mimetic TBAP and catalase. Free Radicals 49-61 superoxide dismutase 2 Homo sapiens 85-115 18594523-4 2008 Knockdown of MnSOD by small-interfering RNA (siRNA) led to an increase in superoxide generation and sensitisation of ovarian cancer cells to the two front-line anti-cancer agents doxorubicin and paclitaxel whose action involved free-radical generation. Free Radicals 228-240 superoxide dismutase 2 Homo sapiens 13-18 18489268-7 2006 As MnSOD is a major inducible free-radical scavenger in skin, these results suggest that the Vfe could induce skin cells to produce their own endogenous protective defences in vivo against both exogenous environmental stressors such as UV irradiation or microflora as well as to combat endogenous sources of deleterious free radicals involved in skin ageing. Free Radicals 320-333 superoxide dismutase 2 Homo sapiens 3-8 17331249-2 2007 SOD2 polymorphisms are of interest because of their potential roles in the modulation of free radical-mediated macromolecular damage during aging. Free Radicals 89-101 superoxide dismutase 2 Homo sapiens 0-4 16141349-5 2006 Essentially all of these events were reversed by free radical scavengers such as the manganese superoxide dismutase (MnSOD) mimetic TBAP and catalase. Free Radicals 49-61 superoxide dismutase 2 Homo sapiens 117-122 15337840-6 2004 The downregulation of the MnSOD expression may lead to an increase of free-radical production and thus explain why the cells in the chronic stress model were more vulnerable to other oxidative stress influences. Free Radicals 70-82 superoxide dismutase 2 Homo sapiens 26-31 15039138-3 2004 One of the most important free radical scavenging enzymes, mitochondrial manganese superoxide dismutase (MnSOD), has been shown to be elevated in mesothelioma (K. Kahlos et al., 1998, Am. Free Radicals 26-38 superoxide dismutase 2 Homo sapiens 73-103 15039138-3 2004 One of the most important free radical scavenging enzymes, mitochondrial manganese superoxide dismutase (MnSOD), has been shown to be elevated in mesothelioma (K. Kahlos et al., 1998, Am. Free Radicals 26-38 superoxide dismutase 2 Homo sapiens 105-110 16024627-3 2005 Manganese superoxide dismutase (MnSOD) is an important antioxidant enzyme encoded by the SOD2 gene that attenuates oxidative free radicals in the mitochondria by catalyzing the formation of hydrogen peroxide from superoxide radicals. Free Radicals 125-138 superoxide dismutase 2 Homo sapiens 0-30 16024627-3 2005 Manganese superoxide dismutase (MnSOD) is an important antioxidant enzyme encoded by the SOD2 gene that attenuates oxidative free radicals in the mitochondria by catalyzing the formation of hydrogen peroxide from superoxide radicals. Free Radicals 125-138 superoxide dismutase 2 Homo sapiens 32-37 16024627-3 2005 Manganese superoxide dismutase (MnSOD) is an important antioxidant enzyme encoded by the SOD2 gene that attenuates oxidative free radicals in the mitochondria by catalyzing the formation of hydrogen peroxide from superoxide radicals. Free Radicals 125-138 superoxide dismutase 2 Homo sapiens 89-93 1682406-0 1991 Elevated level of serum Mn-superoxide dismutase in patients with primary biliary cirrhosis: possible involvement of free radicals in the pathogenesis in primary biliary cirrhosis. Free Radicals 116-129 superoxide dismutase 2 Homo sapiens 24-47 10882843-7 2000 In conjunction with previous findings of increased free radicals and decreased SOD activities in TD subjects, these results suggest that the -9Ala (high activity) MnSOD allele may play a role in protecting against susceptibility to TD in schizophrenics. Free Radicals 51-64 superoxide dismutase 2 Homo sapiens 163-168 10765000-1 1999 To investigate whether the two free-radical scavengers, Cu, Zn- and Mn-superoxide dismutase (SOD), are changed in leukocytes of diabetic patients, and the alteration of these enzymes correlates with the diabetic state, we measured the activity and concentration of these enzymes in leukocytes from diabetic patients. Free Radicals 31-43 superoxide dismutase 2 Homo sapiens 93-96 33124528-2 2021 Manganese superoxide dismutase (MnSOD), one of the most important antioxidases in the human body, plays a key role in maintaining the balance of free radicals in the human body. Free Radicals 145-158 superoxide dismutase 2 Homo sapiens 0-30 33124528-2 2021 Manganese superoxide dismutase (MnSOD), one of the most important antioxidases in the human body, plays a key role in maintaining the balance of free radicals in the human body. Free Radicals 145-158 superoxide dismutase 2 Homo sapiens 32-37 30225256-2 2018 Manganese superoxide dismutase (MnSOD), catalase (CAT), and glutathione peroxidase-1 (GPx1) have evolved to address primary defense against free radical mediated damage in mitochondria. Free Radicals 140-152 superoxide dismutase 2 Homo sapiens 0-30 30225256-2 2018 Manganese superoxide dismutase (MnSOD), catalase (CAT), and glutathione peroxidase-1 (GPx1) have evolved to address primary defense against free radical mediated damage in mitochondria. Free Radicals 140-152 superoxide dismutase 2 Homo sapiens 32-37 30471001-3 2019 Among endogenous antioxidants, SOD constitutes the first line of natural defence against pathological effects induced by an excess of free radicals. Free Radicals 134-147 superoxide dismutase 2 Homo sapiens 31-34