PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11557753-6 2001 We report that sanglifehrin A is capable of activating the tumor suppressor gene p53 at the transcription level, leading to up-regulation of p21 that then binds and inhibits the cylcinE-Cdk2 complex. sanglifehrin A 15-29 cyclin dependent kinase inhibitor 1A Homo sapiens 141-144