PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23710625-5 2013 In the syngeneic Lewis-to-Lewis rat model of kidney transplantation, xenon exposure to donors before graft retrieval or to recipients after engraftment decreased caspase-3 expression, localized HMGB-1 within nuclei and prevented TLR-4/NF-kappaB activation in tubular cells; serum pro-inflammatory cytokines IL-1beta, IL-6 and TNF-alpha were reduced and renal function was preserved. Xenon 69-74 interleukin 1 beta Rattus norvegicus 307-315