PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 737193-8 1978 These results are interpreted to indicate that 7-ketocholesterol, besides affecting sterol synthesis at the level to 3-hydroxy-3-methylglutaryl coenzyme A reductase, must also affect sterol synthesis at another step further along the synthetic pathway. 7-ketocholesterol 47-64 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus 117-164 833506-6 1977 Similar treatment of the animals with 7-ketocholesterol, a cholesterol derivative reported to repress HMG CoA reductase activity in tissue cultures, produced no appreciable difference in reductase activity or serum steroid levels in vivo. 7-ketocholesterol 38-55 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus 102-119