PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19429117-5 2009 ApoD also attenuated the increase in oxidative products of arachidonic acid and cholesterol, F(2)-isoprostanes and 7-ketocholesterol, respectively, after kainate treatment. 7-ketocholesterol 115-132 apolipoprotein D Homo sapiens 0-4 19429117-0 2009 Apolipoprotein D modulates F2-isoprostane and 7-ketocholesterol formation and has a neuroprotective effect on organotypic hippocampal cultures after kainate-induced excitotoxic injury. 7-ketocholesterol 46-63 apolipoprotein D Homo sapiens 0-16 19429117-6 2009 In view of the molecular structure of apoD which consists of an eight stranded beta barrel that forms a binding pocket for a number of small hydrophobic molecules, we propose that apoD promotes its neuroprotective effects by binding to arachidonic acid and cholesterol thus preventing their oxidation to neurotoxic products such as 4-hydroxynonenal (4-HNE) and 7-ketocholesterol. 7-ketocholesterol 361-378 apolipoprotein D Homo sapiens 38-42 19429117-6 2009 In view of the molecular structure of apoD which consists of an eight stranded beta barrel that forms a binding pocket for a number of small hydrophobic molecules, we propose that apoD promotes its neuroprotective effects by binding to arachidonic acid and cholesterol thus preventing their oxidation to neurotoxic products such as 4-hydroxynonenal (4-HNE) and 7-ketocholesterol. 7-ketocholesterol 361-378 apolipoprotein D Homo sapiens 180-184