PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26315049-5 2015 This phenotypic change in CD38-/- CAMs was enhanced by 7-ketocholesterol (7-Ket), an atherogenic stimulus. 7-ketocholesterol 55-72 CD38 antigen Mus musculus 26-30 26315049-14 2015 CONCLUSION: Taken together, these results suggest that CD38 activity is required for 7-Ket-induced Ca2+ and consequently O2-. 7-ketocholesterol 85-90 CD38 antigen Mus musculus 55-59 26315049-5 2015 This phenotypic change in CD38-/- CAMs was enhanced by 7-ketocholesterol (7-Ket), an atherogenic stimulus. 7-ketocholesterol 74-79 CD38 antigen Mus musculus 26-30 26315049-8 2015 In contrast, the overexpression of Nrf2 gene abolished 7-Ket-induced dedifferentiation in CD38-/- CAMs. 7-ketocholesterol 55-60 CD38 antigen Mus musculus 90-94 26315049-10 2015 It was demonstrated that in CD38-/- CAMs, 7-Ket failed to stimulate the production of O2-., while in CD38+/+ CAMs 7-Ket induced marked O2-. 7-ketocholesterol 114-119 CD38 antigen Mus musculus 101-105 24445604-8 2014 Mechanistically, CD38 gene deletion markedly inhibited 7-Ket-induced dynein activation and autophagosome trafficking, which were associated with attenuated lysosomal Ca(2+) release. 7-ketocholesterol 55-60 CD38 antigen Mus musculus 17-21 24445604-5 2014 In primary cultured CAMs, CD38 gene deletion markedly enhanced 7-ketocholesterol (7-Ket, an atherogenic stimulus and autophagy inducer)-induced accumulation of autophagosomes and increased expression of an autophagic marker, LC3B. 7-ketocholesterol 63-80 CD38 antigen Mus musculus 26-30 24445604-5 2014 In primary cultured CAMs, CD38 gene deletion markedly enhanced 7-ketocholesterol (7-Ket, an atherogenic stimulus and autophagy inducer)-induced accumulation of autophagosomes and increased expression of an autophagic marker, LC3B. 7-ketocholesterol 82-87 CD38 antigen Mus musculus 26-30 24445604-7 2014 Further, 7-Ket-induced formation of autophagolysosomes was markedly attenuated in CD38(-/-) CAMs compared with CD38(+/+) CAMs. 7-ketocholesterol 9-14 CD38 antigen Mus musculus 82-86 24445604-7 2014 Further, 7-Ket-induced formation of autophagolysosomes was markedly attenuated in CD38(-/-) CAMs compared with CD38(+/+) CAMs. 7-ketocholesterol 9-14 CD38 antigen Mus musculus 111-115