PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8068724-0	1994	The effect of dietary 7-ketocholesterol, inhibitor of sterol synthesis, on hepatic microsomal cholesterol 7 alpha-hydroxylase activity in rat.	7-ketocholesterol	22-39	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	94-125	
8354276-0	1993	Cholesterol 7 alpha-hydroxylase is up-regulated by the competitive inhibitor 7-oxocholesterol in rat liver.	7-ketocholesterol	77-93	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	0-31	
8354276-5	1993	Addition of 7-oxocholesterol to liver microsomes from normal rats in amounts corresponding to those present in microsomes from 7-oxocholesterol-treated rats inhibited the cholesterol 7 alpha-hydroxylase activity by about 75%.	7-ketocholesterol	12-28	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	171-202	
8354276-5	1993	Addition of 7-oxocholesterol to liver microsomes from normal rats in amounts corresponding to those present in microsomes from 7-oxocholesterol-treated rats inhibited the cholesterol 7 alpha-hydroxylase activity by about 75%.	7-ketocholesterol	127-143	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	171-202	
8354276-8	1993	It is concluded that treatment with the competitive inhibitor 7-oxocholesterol leads to a reduced bile acid biosynthesis and, as a consequence of reduced bile acid inhibition, a compensatory increase in cholesterol 7 alpha-hydroxylase synthesis.	7-ketocholesterol	62-78	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	203-234	
4055743-9	1985	By contrast, 7-ketocholesterol and 20 alpha-hydroxycholesterol strongly inhibited cholesterol 7 alpha-hydroxylase activity at low concentrations (10 microM).	7-ketocholesterol	13-30	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	82-113	
6833879-4	1983	The activity of cholesterol 7alpha-hydroxylase was also significantly inhibited by 7beta-hydroxycholesterol (38%) and 7-ketocholesterol (35%) at concentrations of 1 micro M, and by 10 micro M 7alpha-hydroxycholesterol (35%), 25alpha-hydroxycholesterol (32%), and 5-cholenic acid-3beta-ol (27%).	7-ketocholesterol	118-135	cytochrome P450 family 7 subfamily A member 1	Rattus norvegicus	16-46