PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15720835-2	2004	7-ketocholesterol enhances surface expression of ICAM-1 and VCAM-1 as determined by EIA, induces their mRNA expression by RT-PCR, and stimulates adhesiveness of HAECs to U937 monocytic cells.	7-ketocholesterol	0-17	vascular cell adhesion molecule 1	Homo sapiens	60-66	
16919261-2	2006	The objectives of the present study were to determine the effects of azelnidipine, a new calcium channel blocker, on the expression of VCAM-1 induced by 7-ketocholesterol, components of ox-LDL, and tumor necrosis factor-alpha (TNF-alpha).	7-ketocholesterol	153-170	vascular cell adhesion molecule 1	Homo sapiens	135-141	
16919261-6	2006	The surface expression and mRNA levels of VCAM-1 were determined by enzyme immunoassay and RT-PCR performed on endothelial cell monolayers stimulated with 7-ketocholesterol or TNF-alpha.	7-ketocholesterol	155-172	vascular cell adhesion molecule 1	Homo sapiens	42-48	
16919261-13	2006	These results suggest that azelnidipine works as an anti-atherogenic agent by inhibiting the reactive oxygen species-dependent expression of VCAM-1 induced by 7-ketocholesterol and TNF-alpha.	7-ketocholesterol	159-176	vascular cell adhesion molecule 1	Homo sapiens	141-147	
15720835-6	2004	In conclusion, this study suggests that the endothelial adhesiveness to monocytic cells that was increased by 7-ketocholesterol was associated with enhanced expression of ICAM-1 and VCAM-1 mediated by ROS production.	7-ketocholesterol	110-127	vascular cell adhesion molecule 1	Homo sapiens	182-188	
30063760-4	2018	7-Ketocholesterol enhanced the expression of E-selectin, ICAM-1, and VCAM-1 proteins.	7-ketocholesterol	0-17	vascular cell adhesion molecule 1	Homo sapiens	69-75	
15720835-4	2004	Although the surface expression of ICAM-1 and VCAM-1 on HAECs treated with 7-ketocholesterol increased in a time-dependent manner, alpha-tocopherol inhibited this increase of the surface expression of ICAM-1 and VCAM-1.	7-ketocholesterol	75-92	vascular cell adhesion molecule 1	Homo sapiens	46-52	
15720835-4	2004	Although the surface expression of ICAM-1 and VCAM-1 on HAECs treated with 7-ketocholesterol increased in a time-dependent manner, alpha-tocopherol inhibited this increase of the surface expression of ICAM-1 and VCAM-1.	7-ketocholesterol	75-92	vascular cell adhesion molecule 1	Homo sapiens	212-218	
11325610-1	2001	Treatment of human umbilical vein endothelial cells (HUVECs) with 7-ketocholesterol resulted in an increased release of soluble vascular cell adhesion molecule-1 (VCAM-1) into culture medium.	7-ketocholesterol	66-83	vascular cell adhesion molecule 1	Homo sapiens	128-161	
11325610-1	2001	Treatment of human umbilical vein endothelial cells (HUVECs) with 7-ketocholesterol resulted in an increased release of soluble vascular cell adhesion molecule-1 (VCAM-1) into culture medium.	7-ketocholesterol	66-83	vascular cell adhesion molecule 1	Homo sapiens	163-169	
11325610-4	2001	Western blot analysis revealed that soluble VCAM-1, in the conditioned medium of both 7-ketocholesterol-stimulated and control cells, had a molecular size of 100 kDa.	7-ketocholesterol	86-103	vascular cell adhesion molecule 1	Homo sapiens	44-50	
11325610-5	2001	Stimulation of the TNF-alpha-treated HUVECs with 7-ketocholesterol further increased the levels of soluble VCAM-1 in the culture medium.	7-ketocholesterol	49-66	vascular cell adhesion molecule 1	Homo sapiens	107-113	
11325610-7	2001	Pretreatment of the cells with tissue inhibitor of membrane metalloproteinase-2 (TIMP-2) completely inhibited the release of VCAM-1 in response to 7-ketocholesterol but TIMP-1 had no effect.	7-ketocholesterol	147-164	vascular cell adhesion molecule 1	Homo sapiens	125-131	
11325610-10	2001	We conclude that 7-ketocholesterol releases VCAM-1 from the endothelium probably by a proteolytic process.	7-ketocholesterol	17-34	vascular cell adhesion molecule 1	Homo sapiens	44-50	
11686311-6	2001	The level of soluble VCAM-1 showed significant correlation between the values of 7-ketocholesterol (r=0.42, p=0.024), TC (r=0.42, p=0.014) and LDL-C (r=0.38, p=0.044).	7-ketocholesterol	81-98	vascular cell adhesion molecule 1	Homo sapiens	21-27