PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34936813-0 2022 Mammalian Target of Rapamycin Inhibitor Rapamycin Alleviates 7-Ketocholesterol Induced Inflammatory Responses and Vascular Endothelial Growth Factor Elevation by Regulating MAPK Pathway in Human Retinal Pigment Epithelium Cells. 7-ketocholesterol 61-78 mechanistic target of rapamycin kinase Homo sapiens 0-29 29029490-0 2017 7-ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic activity and mTOR pathway. 7-ketocholesterol 0-17 mechanistic target of rapamycin kinase Homo sapiens 126-130 23792120-0 2013 7-Ketocholesterol induces P-glycoprotein through PI3K/mTOR signaling in hepatoma cells. 7-ketocholesterol 0-17 mechanistic target of rapamycin kinase Homo sapiens 54-58 34936813-10 2022 Conclusions: Inhibition of mTOR signaling pathway suppressed the elevation of inflammatory cytokines IL-6, IL-8, and the angiogenic agent VEGF induced by 7-KC. 7-ketocholesterol 154-158 mechanistic target of rapamycin kinase Homo sapiens 27-31 34936813-1 2022 Purpose: To validate the protective effect of a mammalian target of rapamycin (mTOR) inhibitor on human retinal pigment epithelium (RPE) cells challenged with 7-ketocholesterol (7-KC) and explored the underlying mechanisms. 7-ketocholesterol 159-176 mechanistic target of rapamycin kinase Homo sapiens 48-77 34936813-1 2022 Purpose: To validate the protective effect of a mammalian target of rapamycin (mTOR) inhibitor on human retinal pigment epithelium (RPE) cells challenged with 7-ketocholesterol (7-KC) and explored the underlying mechanisms. 7-ketocholesterol 159-176 mechanistic target of rapamycin kinase Homo sapiens 79-83 34936813-1 2022 Purpose: To validate the protective effect of a mammalian target of rapamycin (mTOR) inhibitor on human retinal pigment epithelium (RPE) cells challenged with 7-ketocholesterol (7-KC) and explored the underlying mechanisms. 7-ketocholesterol 178-182 mechanistic target of rapamycin kinase Homo sapiens 48-77 34936813-1 2022 Purpose: To validate the protective effect of a mammalian target of rapamycin (mTOR) inhibitor on human retinal pigment epithelium (RPE) cells challenged with 7-ketocholesterol (7-KC) and explored the underlying mechanisms. 7-ketocholesterol 178-182 mechanistic target of rapamycin kinase Homo sapiens 79-83