PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17072090-4 2006 Uptake of tetraethylammonium by OCTN1 was much higher in HEK293/PDZK1 cells, compared with that in the parent HEK293 cells, the uptake in HEK293/PDZK1-E195K cells showing middle range between the two values. Tetraethylammonium 10-28 solute carrier family 22 member 4 Homo sapiens 32-37 20601551-4 2010 In addition, uptake of [(3)H]ERGO by human embryonic kidney 293 cells heterologously expressing OCTN1 gene product and uptake of [(3)H]ERGO at the apical surface of intestinal everted sacs from wild-type mice were inhibited by OCTN1 substrates, tetraethylammonium and verapamil. Tetraethylammonium 245-263 solute carrier family 22 member 4 Homo sapiens 96-101 15795384-2 2005 SLC22A4 codes for an integral membrane protein, OCTN1, that has been presumed to carry organic cations like tetraethylammonium across the plasma membrane. Tetraethylammonium 108-126 solute carrier family 22 member 4 Homo sapiens 0-7 15795384-2 2005 SLC22A4 codes for an integral membrane protein, OCTN1, that has been presumed to carry organic cations like tetraethylammonium across the plasma membrane. Tetraethylammonium 108-126 solute carrier family 22 member 4 Homo sapiens 48-53 15795384-9 2005 Because ET is transported >100 times more efficiently than tetraethylammonium and carnitine, we propose the functional name ETT (ET transporter) instead of OCTN1. Tetraethylammonium 62-80 solute carrier family 22 member 4 Homo sapiens 127-130 15459889-6 2004 The Km and Vmax values for tetraethylammonium (TEA) uptake by T306I were similar to those of the wild-type even when the Vmax value was normalized for the expression level of OCTN1 protein. Tetraethylammonium 27-45 solute carrier family 22 member 4 Homo sapiens 175-180 15459889-6 2004 The Km and Vmax values for tetraethylammonium (TEA) uptake by T306I were similar to those of the wild-type even when the Vmax value was normalized for the expression level of OCTN1 protein. Tetraethylammonium 47-50 solute carrier family 22 member 4 Homo sapiens 175-180 10215651-4 1999 In addition, when OCTN1 was expressed in HEK293 cells, efflux of TEA from the cells was pH dependent, with an accelerated rate at acidic external medium pH. Tetraethylammonium 65-68 solute carrier family 22 member 4 Homo sapiens 18-23 15832501-1 2004 OCTN1 (SLC22A4) transports cationic compounds such as tetraethylammonium in a pH-sensitive and sodium-independent manner in cultured cells, and is expressed in wide variety of tissues, including kidney, muscle, placenta, heart, and others. Tetraethylammonium 54-72 solute carrier family 22 member 4 Homo sapiens 0-5 15832501-1 2004 OCTN1 (SLC22A4) transports cationic compounds such as tetraethylammonium in a pH-sensitive and sodium-independent manner in cultured cells, and is expressed in wide variety of tissues, including kidney, muscle, placenta, heart, and others. Tetraethylammonium 54-72 solute carrier family 22 member 4 Homo sapiens 7-14 15832501-3 2004 Uptake of [14C]tetraethylammonium by membrane vesicles prepared from HEK293 cells stably transfected with human OCTN1 cDNA was osmolarity-sensitive, and the Km of tetraethylammonium was 1.28 mM at intravesicular and extravesicular pH values of 6.0 and 7.4, respectively. Tetraethylammonium 15-33 solute carrier family 22 member 4 Homo sapiens 112-117 10215651-8 1999 OCTN1-mediated [14C]TEA uptake was inhibited by various organic cations such as cimetidine, procainamide, pyrilamine, quinidine, quinine, and verapamil. Tetraethylammonium 20-23 solute carrier family 22 member 4 Homo sapiens 0-5