PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29996627-5 2018 Our data indicated that the innate and adaptive immune responses was elicited by successive immunizations with pVAX-HSP60 DNA, showing apparent increases of CD3e+CD4+ and CD3e+CD8a+ T cells in spleen tissues of the HSP60 DNA-immunized mice (24.70+-1.23% and 10.90+-0.89%, P<0.05) and higher levels of specific antibodies in sera. Adenosine Monophosphate 274-277 heat shock protein 1 (chaperonin) Mus musculus 116-121 31477750-7 2019 Metabolomic analysis revealed that HSP60 silencing resulted in a more than 100-fold increase in cellular adenine levels, leading to increased adenosine monophosphate and an activated AMPK pathway, and consequently reduced mTORC1-mediated S6K and 4EBP1 phosphorylation to inhibit protein synthesis that suppressed the proliferation of OC cells. Adenosine Monophosphate 142-165 heat shock protein 1 (chaperonin) Mus musculus 35-40