PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29693558-3 2018 Previous reports have identified the expression of two of the five receptors for S1P on mast cells, S1P1 and S1P2, with functions in FcεRI-mediated chemotaxis and degranulation, respectively. Adenosine Monophosphate 136-139 sphingosine-1-phosphate receptor 1 Mus musculus 81-84 12557151-1 2003 BACKGROUND & AIMS: Sphingosine 1-phosphate (S1P), a ligand for G protein-coupled endothelial differentiation gene-1 (Edg-1), Edg-3, Edg-5, Edg-6, and Edg-8, elicits a variety of responses by cells. Adenosine Monophosphate 12-15 sphingosine-1-phosphate receptor 1 Mus musculus 48-51 29757216-4 2018 Herein, we observed lower sphingosine-1-phosphate receptor 1 (S1P1) expression in NOD mouse thymocytes when compared with controls, mainly in the mature SP CD4+CD62Lhi and CD8+CD62Lhi subpopulations bearing the CD49e− phenotype. Adenosine Monophosphate 217-220 sphingosine-1-phosphate receptor 1 Mus musculus 26-60 29757216-4 2018 Herein, we observed lower sphingosine-1-phosphate receptor 1 (S1P1) expression in NOD mouse thymocytes when compared with controls, mainly in the mature SP CD4+CD62Lhi and CD8+CD62Lhi subpopulations bearing the CD49e− phenotype. Adenosine Monophosphate 217-220 sphingosine-1-phosphate receptor 1 Mus musculus 62-66 29693558-3 2018 Previous reports have identified the expression of two of the five receptors for S1P on mast cells, S1P1 and S1P2, with functions in FcεRI-mediated chemotaxis and degranulation, respectively. Adenosine Monophosphate 136-139 sphingosine-1-phosphate receptor 1 Mus musculus 100-113 27343196-0 2016 Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium. Adenosine Monophosphate 112-115 sphingosine-1-phosphate receptor 1 Mus musculus 103-106 27343196-0 2016 Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium. Adenosine Monophosphate 112-115 sphingosine-1-phosphate receptor 1 Mus musculus 107-111 27343196-8 2016 Hyperoxia stimulated S1P accumulation in human lung microvascular endothelial cells (HLMVECs), and downregulation of S1P transporter spinster homolog 2 (Spns2) or S1P receptors S1P1&2, but not S1P3, using specific siRNA attenuated hyperoxia-induced p47(phox) translocation to cell periphery and ROS generation in HLMVECs. Adenosine Monophosphate 182-185 sphingosine-1-phosphate receptor 1 Mus musculus 117-120 27343196-8 2016 Hyperoxia stimulated S1P accumulation in human lung microvascular endothelial cells (HLMVECs), and downregulation of S1P transporter spinster homolog 2 (Spns2) or S1P receptors S1P1&2, but not S1P3, using specific siRNA attenuated hyperoxia-induced p47(phox) translocation to cell periphery and ROS generation in HLMVECs. Adenosine Monophosphate 182-185 sphingosine-1-phosphate receptor 1 Mus musculus 117-120 27343196-9 2016 These results suggest a role for Spns2 and S1P1&2 in hyperoxia-mediated ROS generation. Adenosine Monophosphate 48-51 sphingosine-1-phosphate receptor 1 Mus musculus 43-47 25446881-3 2015 However, the in vivo contribution of S1P, regulated by its synthesis catalyzed by Sphingosine kinases (SphKs) 1 & 2 and catabolism by S1P phosphatases and S1P lyase (S1PL), in the pathogenesis of pulmonary fibrosis is not well defined. Adenosine Monophosphate 113-116 sphingosine-1-phosphate receptor 1 Mus musculus 37-40 23466305-1 2013 BACKGROUND & AIMS: Sphingosine kinase (SphK)/sphingosine 1-phosphate (S1P)/S1P receptor (S1PR) axis is involved in multiple biological processes, including liver fibrosis. Adenosine Monophosphate 12-15 sphingosine-1-phosphate receptor 1 Mus musculus 74-77 23466305-1 2013 BACKGROUND & AIMS: Sphingosine kinase (SphK)/sphingosine 1-phosphate (S1P)/S1P receptor (S1PR) axis is involved in multiple biological processes, including liver fibrosis. Adenosine Monophosphate 12-15 sphingosine-1-phosphate receptor 1 Mus musculus 79-82